Commercial Highlights and Pipeline
Sales for the Wegovy pill reached DKK 5,394 million in the third quarter. According to the company, the Wegovy pill has been launched in the US, UAE, UK, and Germany, with recent launches in four additional countries bringing the total number of launched markets to eight. Novo Nordisk reports that the Wegovy franchise maintains a US market share of more than 50% in the branded obesity market based on new patient starts.
Regarding the Ozempic pill, which launched in the US in May, the company reports "encouraging early momentum," noting that weekly new-to-brand prescriptions (NBRx) are currently up approximately 100% compared to pre-launch levels under the Rybelsus brand.
In its clinical pipeline, Novo Nordisk reported the following:
- CagriSema (1.0/1.0 mg): In the REDEFINE 9 trial, it delivered a 21% weight loss at week 68. In the REIMAGINE 5 trial for adults with type 2 diabetes and obesity, it achieved a 12.4% weight loss compared with 9.1% for tirzepatide 5 mg.
- Oral zenagamtide: The AMAZE 9 phase 3 trial was initiated in September.
- Frehemgo (denecimig): Received a positive CHMP opinion on 17 September. The company plans the first European launches around the turn of the year, pending full EU approval. A US launch is expected in H1 2027, pending regulatory decision.
"We delivered a stronger-than-expected third quarter and are raising our full-year outlook for adjusted sales and adjusted operating profit," said Mike Doustdar, president and CEO of Novo.